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Support

Our customer service and technical support teams are ready to take your call and address any queries or problems you may have.

Vaccine Response

The immune response of an individual can vary depending on the nature of the antigen initiating the response. Failure to produce the appropriate specific antibody response or the production of functionally inactive antibodies may result in recurrent and/or persistent infection. The immune system is able to recognize protein antigens adequately from the first year of life and this is the basis...

IgA Subclasses

IgA is responsible for mucosal immunity and is therefore the first line of defense for the majority of infections. Normal serum concentrations of both IgA subclasses may be very low therefore a sensitive, reproducible assay is essential, particularly for pediatric samples. Our IgA subclass assays also utilize highly specific high-affinity, polyclonal antisera and latex-enhanced reagents to...

Plasma Screening

The accurate measurement of specific antibodies is also important during the manufacturing of therapeutic immunoglobulin and hyperimmune products. Plasma donors are screened for the presence of specific antibodies and donor units with high levels are selected as raw material for the production of therapeutic immunoglobulin products. The kits have been designed specifically for this purpose and...

Complement

The complement system is a complex series of proteins that act as a cascade. They react in the sequence C1q, C1r, C1s, C4, C2, C3, C5, C6, C7, C8, C9; many requiring proteolytic cleavage to become active. The cascade is activated either via the Classical Pathway, the Alternative Pathway or the Lectin Pathway. Complement proteins are assayed to measure complement consumption and to diagnose...

Scientific Support

A team of Binding Site's Medical Science Liaison staff are available to support you with clinical and educational support. 1. Educational seminars We can provide educational seminars at your hospital, laboratory or conference. Please contact us scientific.support@bindingsite.co.uk for more information. 2. Clinical Studies We can help you initiate and evaluate clinical studies using Binding Site...

Customer Support

Our team of technical experts is dedicated to supporting our customers and pride themselves in providing an exemplary customer experience. We offer unrivalled after sales support, built on three key areas: 1. Product Installation and Evaluation Swift and efficient integration of products into your laboratory with minimal disruption to routine workflow, ensuring optimal product performance and...

Session Overview: The role of Free Light Chains in the Diagnosis of Monoclonal Gammopathies

Dr Katzmann began his presentation by reminding the audience that the monoclonal gammopathies are a diverse group of diseases. These plasma cell disorders secrete a wide range of monoclonal proteins, varying significantly both in molecular weight and in the unique variable region sequences. As such, there are three tests currently used to diagnose monoclonal gammopathies &ndash; protein...

Incidence of Free Light Chain Escape in Multiple Myeloma, Why is it Increasing?

Four types of relapse are commonly seen with Multiple Myeloma. At the beginning of his presentation, Mark Drayson described a study in which 35% of the study participants showed an increase in both paraprotein and free light chain levels, 50% showed only an increase in paraprotein levels, 5% showed a small or no increase in paraprotein and free light chains and 10% relapsed with an increase in...

Dr Dispenzieri on the groundbreaking changes in myeloma diagnosis

Dr. Dispenzieri, Professor of Medicine in the Division of Hematology at the Mayo Clinic, discusses the International Myeloma Working Group guidelines for the diagnosis of myeloma, and the new biomarker status of the Freelite assay. In this video Dr. Dispenzieri talks about: • Why the new guidelines are groundbreaking • The role of biomarkers in the new guidelines • Advice for clinicians •...